
Containment Laboratory Ventilation Recovery for International Research Facility
Restoring Stability to a Critical Research Facility
A leading international research institution operating a Containment Level 3 (CL3) laboratory facility in West Africa experienced persistent environmental alarms and pressure instability affecting critical laboratory operations.
The facility supported essential regional research activities and relied heavily on specialised containment ventilation infrastructure designed to maintain environmental stability, pressure control, and operational safety.
Due to ongoing system instability and limited availability of the original specialist support providers, Aeris Flow was engaged to travel internationally and provide independent technical investigation, containment recovery, and environmental stabilisation support.
Project Highlights
Containment Level 3 Research Laboratory
- • Ventilation troubleshooting
- • Containment assessment
- • Pressure recovery
- • HEPA filtration replacement
- • Environmental balancing
- • Strategic consultancy
International Research & Healthcare
Diagnosing Pressure Instability Within a High-Containment Environment
Initial investigations identified:
- Persistent pressure alarms
- Ventilation instability
- Inadequate pressure differentials
- Reduced airflow performance
- Saturated pre-filtration systems
- Restricted HEPA performance
- Regional environmental challenges
The complexity of the original ventilation and control strategy created operational and maintenance challenges for the local engineering teams.
"Prolonged operational demand forced the entire facility to rely on a single system which had become heavily saturated."
One of the primary air handling units was non-operational, forcing the facility to rely on a single system that had become heavily saturated due to regional environmental conditions.
Specialist Ventilation Recovery & Environmental Stabilisation
Aeris Flow carried out a technical investigation combining performance assessment, stability analysis, and sensor calibration verification.
Key actions included:
- Pressure stability analysis
- Alarm system investigation
- Air handling unit inspections
- Filtration system assessment
- Environmental balancing
During the investigation, replacement filtration systems previously believed to be unavailable were successfully identified and recovered from on-site storage.
All identified deficiencies were documented, rectified, and independently verified prior to returning the facility to operational service.

Sealability Recovery & Leakage Investigation
Aeris Flow carried out a detailed containment fabric and sealability assessment to evaluate whether uncontrolled leakage paths within the laboratory envelope were contributing to the pressure instability.
Targeted containment sealing and integrity improvement works were performed across affected areas prior to final environmental rebalancing activities.
The inspection identified multiple significant leakage paths capable of compromising pressure retention and future fumigation effectiveness.

Simplifying Long-Term Operational Sustainability
Aeris Flow identified that the original containment ventilation strategy was unnecessarily complex for the local operational environment and maintenance capability.
A simplified strategy was developed to improve long-term reliability, reduce maintenance complexity, and improve the sustainability of local support capabilities.
Restoring Critical Research Operations
Through specialist troubleshooting, containment integrity improvements, filtration recovery, and environmental rebalancing, Aeris Flow successfully restored operational stability to the facility.
The project successfully stabilised containment performance, eliminated persistent alarms, and restored operational continuity for ongoing research activities.

Need Support With Containment Ventilation or Critical Environmental Systems?
Aeris Flow provides specialist troubleshooting, environmental recovery, and containment laboratory support for regulated and high-risk environments worldwide.
Speak to a Technical Specialist